Hotels in Medical Center Area, Boston

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Our top choices for Medical Center Area hotels

The Inn at Longwood Medical

The Inn at Longwood Medical
3.5 star property
Medical Center Area
8.4 out of 10, Very good, (1,001 reviews)
"Very Close to B&W Hospital. Good Restaurant in Lobby."
United States
Richard
The price is CA $382
CA $485 total
includes taxes & fees
May 23 - May 24
The Inn at Longwood Medical

citizenM Boston Back Bay

citizenM Boston Back Bay
4.0 star property
1.6 km from Medical Center Area
9.4 out of 10, Exceptional, (2,677 reviews)
"Easy walk to Fenway park. Lots of great restaurants and stores near by. We enjoyed our stay."
United States
Stephanie
The price is CA $232
CA $271 total
includes taxes & fees
May 25 - May 26
citizenM Boston Back Bay

Hyatt Place Boston/Seaport District

Hyatt Place Boston/Seaport District
3.0 star property
Seaport District, 5.6 km from Medical Center Area
9.4 out of 10, Exceptional, (2,374 reviews)
"Awesome hotel! Great location!!!"
Canada
Craig
The price is CA $274
CA $319 total
includes taxes & fees
May 25 - May 26
Hyatt Place Boston/Seaport District

The Midtown Hotel MOD Collection by Sonesta

The Midtown Hotel MOD Collection by Sonesta
3.0 star property
Prudential - St. Botolph, 1.8 km from Medical Center Area
8.2 out of 10, Very good, (357 reviews)
"Clean and great location would definitely stay there again"
Canada
Howard
The price is CA $287
CA $335 total
includes taxes & fees
May 25 - May 26
The Midtown Hotel MOD Collection by Sonesta

Hyatt Regency Boston

Hyatt Regency Boston
4.0 star property
Downtown Crossing, 3.9 km from Medical Center Area
9.0 out of 10, Wonderful, (2,024 reviews)
"Excellent hotel and great location!"
United States
Toni
The price is CA $232
CA $319 total
includes taxes & fees
May 25 - May 26
Hyatt Regency Boston

Battery Wharf Hotel, Boston Waterfront

Battery Wharf Hotel, Boston Waterfront
4.5 star property
North End, 5.4 km from Medical Center Area
8.8 out of 10, Excellent, (1,826 reviews)
"Great location, great staff. Great view, and great rooms"
United States
Jeannette
The price is CA $190
CA $278 total
includes taxes & fees
May 25 - May 26
Battery Wharf Hotel, Boston Waterfront

Seaport Hotel Boston

Seaport Hotel Boston
4.0 star property
Seaport District, 5.3 km from Medical Center Area
9.6 out of 10, Exceptional, (4,371 reviews)
"Beautiful hotel and staff was great !"
United States
Tonda
The price is CA $318
CA $417 total
includes taxes & fees
May 25 - May 26
Seaport Hotel Boston

Omni Boston Hotel at the Seaport

Omni Boston Hotel at the Seaport
5.0 star property
Seaport District, 5.1 km from Medical Center Area
9.2 out of 10, Wonderful, (4,657 reviews)
"Great stay."
United States
Cassendra
The price is CA $246
CA $343 total
includes taxes & fees
May 29 - May 30
Omni Boston Hotel at the Seaport

The Westin Boston Seaport District

The Westin Boston Seaport District
4.0 star property
Seaport District, 5 km from Medical Center Area
9.2 out of 10, Wonderful, (2,398 reviews)
"Great hotel!"
United States
Andrea
The price is CA $246
CA $351 total
includes taxes & fees
May 29 - May 30
The Westin Boston Seaport District

The Hotel Marblehead

The Hotel Marblehead
3.5 star property
26.1 km from Medical Center Area
9.2 out of 10, Wonderful, (500 reviews)
"Clean room and comfortable beds!"
United States
Adam
The price is CA $233
CA $261 total
includes taxes & fees
May 25 - May 26
The Hotel Marblehead

The Godfrey Hotel Boston

The Godfrey Hotel Boston
4.0 star property
Downtown Crossing, 3.9 km from Medical Center Area
9.4 out of 10, Exceptional, (5,069 reviews)
"very well located property one block from Boston Commons , lots of food options around , staff is awesome ."
United States
Rogerio
The price is CA $283
CA $386 total
includes taxes & fees
May 22 - May 23
The Godfrey Hotel Boston

YOTEL Boston

YOTEL Boston
4.0 star property
4.9 km from Medical Center Area
8.6 out of 10, Excellent, (2,524 reviews)
"Very cool hotel and location!"
United States
Emily
The price is CA $260
CA $375 total
includes taxes & fees
May 29 - May 30
YOTEL Boston

The Dagny Boston

The Dagny Boston
4.0 star property
Boston Financial District, 4.6 km from Medical Center Area
9.4 out of 10, Exceptional, (7,245 reviews)
"Overall great place to stay"
United States
Rob
The price is CA $219
CA $303 total
includes taxes & fees
May 25 - May 26
The Dagny Boston

Aloft by Marriott Boston Seaport District

Aloft by Marriott Boston Seaport District
3.0 star property
Seaport District, 4.9 km from Medical Center Area
8.8 out of 10, Excellent, (1,467 reviews)
"Nice clean hotel, very friendly staff. "
United States
Edith
The price is CA $227
CA $304 total
includes taxes & fees
May 24 - May 25
Aloft by Marriott Boston Seaport District

Harborside Inn Of Boston

Harborside Inn Of Boston
4.0 star property
Boston Financial District, 4.8 km from Medical Center Area
9.2 out of 10, Wonderful, (6,569 reviews)
"Loved the location and the bar lounge."
United States
Yolanda
The price is CA $246
CA $287 total
includes taxes & fees
May 25 - May 26
Harborside Inn Of Boston

Courtyard by Marriott Boston Downtown/North Station

Courtyard by Marriott Boston Downtown/North Station
3.0 star property
West End, 4.7 km from Medical Center Area
9.4 out of 10, Exceptional, (1,341 reviews)
"Well located and excellent staff and larger rooms; also nice view"
United States
Cynthia T
The price is CA $207
CA $241 total
includes taxes & fees
May 25 - May 26
Courtyard by Marriott Boston Downtown/North Station

Hampton by Hilton at the Boston Seaport District

Hampton by Hilton at the Boston Seaport District
3.0 star property
Seaport District, 5.4 km from Medical Center Area
9.2 out of 10, Wonderful, (2,867 reviews)
"A very pleasant stay!"
United States
Judy
The price is CA $234
CA $272 total
includes taxes & fees
May 25 - May 26
Hampton by Hilton at the Boston Seaport District

citizenM Boston North Station

citizenM Boston North Station
4.0 star property
West End, 4.6 km from Medical Center Area
9.4 out of 10, Exceptional, (4,600 reviews)
"Great stay!!"
United States
Tanaychea N
The price is CA $197
CA $229 total
includes taxes & fees
May 25 - May 26
citizenM Boston North Station

Hilton Boston Park Plaza

Hilton Boston Park Plaza
4.0 star property
Bay Village, 3.1 km from Medical Center Area
8.4 out of 10, Very good, (3,106 reviews)
"Great location and nice stay!"
United States
Elizabeth
The price is CA $246
CA $343 total
includes taxes & fees
May 25 - May 26
Hilton Boston Park Plaza

Hampton Inn Boston - Logan Airport

Hampton Inn Boston - Logan Airport
3.0 star property
10.6 km from Medical Center Area
8.2 out of 10, Very good, (5,597 reviews)
"Clean rooms, convenient location"
United States
Raja
The price is CA $177
CA $198 total
includes taxes & fees
May 25 - May 26
Hampton Inn Boston - Logan Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center Area

Find the best Medical Center Area areas and neighborhoods for the activities you enjoy most.

Downtown Boston

Densely packed with highrise buildings, this area boasts landmarks like Custom House Tower and is close to Quincy Market, Faneuil Hall, and the Old State House. Find headquarters of major banks, hotels, and investment firms here.

Back Bay

Victorian brownstone homes and cultural institutions like the Boston Public Library define this area. Shop at Newbury Street, Prudential Center, and Copley Place, or explore sights like Trinity Church and the John Hancock Tower.

Seaport District

Experience a transformed industrial area with office towers, innovation labs, and 78 restaurants. Visit the Institute of Contemporary Art and easily access Downtown Boston via the Evelyn Moakley Bridge.

Beacon Hill

Historic Federal-style rowhouses, gaslit streets, and brick sidewalks create a charming atmosphere. Explore the Boston African American National Historic Site, shop on Charles Street, and easily access MBTA stations.

North End

Indulge in Italian cuisine at numerous restaurants and bakeries, explore historic sites like Old North Church and Paul Revere House, and enjoy performances at NEMPAC and Improv Asylum Theater. Easily accessible via MBTA lines, buses, and ferries.

Top Medical Center Area Hotel Reviews

Frequently asked questions

What are the best hotels in Medical Center Area that travellers recommend?
For highly recommended hotels in the Medical Centre Area, consider The Eliot Hotel, Raffles Boston, The Colonnade Hotel Back Bay, Iris Hotel Boston, and Mandarin Oriental, Boston.

The 4-star The Eliot Hotel, with an impressive 9.6 rating, is frequently praised for its spacious, clean rooms and friendly, helpful staff. Guests appreciate the beautiful suites and excellent service. It is located near The Fens and the Isabella Stewart Gardner Museum.

Raffles Boston, a 5-star hotel rated 9.6, offers exceptional service and attentive staff. Guests enjoy the nice rooms, and its convenient location is a highlight, being just 0.1 km from 200 Clarendon Street. It also features deep soaking bathtubs and rainfall showerheads.

Another excellent choice is The Colonnade Hotel Back Bay, a 4-star hotel with a 9.2 rating. This hotel is commended for its excellent location, friendly staff, and spacious, clean rooms. It also offers convenient parking and great service. The hotel is close to the Minuteman Bikeway.

The 4-star Iris Hotel Boston, rated 9.4, is known for its comfortable, great rooms and excellent amenities. The staff are friendly and helpful, and guests consistently highlight the fantastic service. It is conveniently located near the Brookline Farmers Market.

Finally, the 5-star Mandarin Oriental, Boston, with a 9.4 rating, receives high praise for its amazing staff who are always willing to help. Guests appreciate the perfect, clean rooms and the excellent location. It is situated close to 200 Clarendon Street and The Fens.
What are the best family hotels in Medical Center Area?
For families visiting the Medical Centre Area, several excellent hotels offer amenities and features to ensure a comfortable stay, including Raffles Boston, The Lenox Hotel Boston, Residence Inn by Marriott Boston Back Bay/Fenway, and Four Seasons Hotel One Dalton Street, Boston.

Raffles Boston is a 5-star hotel with an outstanding 9.6 rating. This hotel provides connecting rooms, books and games for children, kids' meals, children's bathrobes, complimentary cribs, and onsite babysitting services. Guests frequently praise the attentive staff, nice rooms, and convenient location, with Innovation District just 2.9 km away and Gibson House Museum 0.7 km away.

Another highly-rated option is The Lenox Hotel Boston, a 4.5-star hotel with a 9.6 rating. It offers complimentary cribs, kids' meals in the restaurant, onsite babysitting, connecting rooms, and rollaway extra beds. The hotel also features a child-friendly window design for added peace of mind. Customers appreciate the friendly and helpful staff, excellent location, and clean rooms.

The 3-star Residence Inn by Marriott Boston Back Bay/Fenway, rated 9.2, is a great choice for families. It provides complimentary rollaway extra beds and cribs, sofa beds, connecting rooms, and a pool. It's conveniently located near The Fens, just 0.3 km away, and the Isabella Stewart Gardner Museum, 0.8 km away. Guests frequently mention the clean rooms, friendly staff, and great breakfast.

The 5-star Four Seasons Hotel One Dalton Street, Boston, with a 9.6 rating, is another excellent family-friendly option. It offers complimentary rollaway extra beds and cribs, connecting rooms, a pool, sofa beds, and kids' meals in the restaurant. The hotel is praised for its exceptional staff, great location, and clean rooms. It is 1.5 km from The Fens and 1.3 km from Gibson House Museum.
What are the best 5-star hotels in Medical Center Area?
For exceptional 5-star accommodation in the Medical Centre Area, consider the Raffles Boston, Mandarin Oriental, Boston, and the Four Seasons Hotel One Dalton Street, Boston.

The 5-star Raffles Boston, with an outstanding 9.6 rating, offers luxurious features such as deep soaking bathtubs, rainfall showerheads, and designer toiletries. Guests frequently praise the attentive staff and great rooms. The hotel also provides 24-hour room service and valet parking, and is conveniently located near 200 Clarendon Street, just 0.1 km away.

Another excellent choice is the 5-star Mandarin Oriental, Boston, rated 9.4. This hotel boasts Frette Italian sheets and premium bedding for a truly comfortable stay, along with 24-hour room service and valet parking. Guests consistently praise the amazing staff and excellent location, with 200 Clarendon Street just 0.6 km away.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, offers a refined experience. It features deep soaking bathtubs, designer toiletries, and premium bedding. The hotel also provides 24-hour room service and valet parking. Travellers regularly highlight the exceptional staff, great facilities, and clean rooms. It is also conveniently located near 200 Clarendon Street, 0.9 km away.
What are the best spa hotels in Medical Center Area?
For an exceptional spa experience in the Medical Centre Area, consider the Mandarin Oriental, Boston, Raffles Boston, Four Seasons Hotel One Dalton Street, Boston, or the Iris Hotel Boston.

The 5-star Mandarin Oriental, Boston, with an impressive 9.4 rating, offers an extensive spa experience including deep tissue, hot stone, and Swedish massages, hydrotherapy treatments, and a steam room. Guests consistently praise the amazing and always willing to help staff, the excellent location, and the perfect, clean rooms. It is conveniently located near 200 Clarendon Street and the Christian Science Plaza.

Another outstanding option is the 5-star Raffles Boston, boasting an excellent 9.6 rating. This hotel provides a full-service spa with a hot tub, steam room, and dedicated treatment rooms for massages and body treatments. Reviewers frequently highlight the attentive staff, nice rooms, and convenient location, being very close to 200 Clarendon Street and Gallery Naga.

The 5-star Four Seasons Hotel One Dalton Street, Boston, also with a 9.6 rating, features a full-service spa offering body wraps, scrubs, manicures, pedicures, and a steam room. Guests consistently praise the exceptional staff, great location, and clean rooms. It's ideally situated near the Christian Science Plaza and Prudential Tower.

For a highly-rated 4-star option, the Iris Hotel Boston, with a 9.4 rating, provides a range of spa services including deep tissue and hot stone massages, aromatherapy, and facial treatments. Travellers appreciate the friendly and helpful staff, comfortable rooms, and excellent location, being close to the John Fitzgerald Kennedy National Historic Site.
What are the top boutique hotels in Medical Center Area?
For a top boutique hotel in the Medical Centre Area, The Westin Copley Place, Boston, a Marriott Hotel is an excellent choice.

This 4-star hotel, with a 9.2 rating, is known for its Art Deco design and offers premium bedding for a comfortable stay. Guests often highlight the convenient location and the friendly, helpful staff. The hotel provides excellent fitness facilities, including a 24-hour fitness centre and on-site yoga and fitness classes. It is also very close to 200 Clarendon Street, just 0.2 km away, and the Prudential Tower, 0.4 km away.
What are the most romantic hotels in Medical Center Area for couples?
For a romantic stay in the Medical Centre Area, several highly-rated hotels offer exceptional experiences for couples, including The Eliot Hotel, Four Seasons Hotel One Dalton Street, Boston, Raffles Boston, and Iris Hotel Boston.

The 4-star Eliot Hotel, with a superb 9.6 rating, is a wonderful choice for couples. It features elegant suites, premium bedding, and designer toiletries. Guests frequently praise the excellent staff and spacious, clean rooms. Dining options for couples are available, and the hotel provides valet parking. It is also conveniently located near the Prudential Tower, just 0.5 km away, and the Christian Science Plaza, 0.6 km away.

Another outstanding option is the 5-star Four Seasons Hotel One Dalton Street, Boston, which also boasts a 9.6 rating. This hotel is situated in a shopping district and offers luxurious amenities such as deep soaking bathtubs, designer toiletries, and 24-hour room service. Couples can enjoy treatment rooms, and guests consistently praise the exceptional staff and facilities. The hotel is very close to the Prudential Tower, only 0.2 km away, and the Christian Science Plaza, 0.3 km away.

The 5-star Raffles Boston, rated 9.6, provides a truly luxurious and romantic experience. It features deep soaking bathtubs, rainfall showerheads, designer toiletries, and fireplaces. Couples can indulge in spa amenities like a hot tub, sauna, and couples treatment rooms. Guests frequently highlight the attentive staff and convenient location. It is just 0.1 km from 200 Clarendon Street and 0.6 km from the Prudential Tower.

Finally, the 4-star Iris Hotel Boston, with a 9.4 rating, is another excellent choice for couples. This hotel offers premium bedding, Frette Italian sheets, champagne service, and private indoor hot tubs for a truly intimate experience. Guests appreciate the friendly and helpful staff, comfortable rooms, and excellent location. It is located 0.7 km from the John Fitzgerald Kennedy National Historic Site.
When is the best time to go to Medical Center Area?
The best time to visit the Medical Center Area is during the late spring (May to June) or early autumn (September to October).

These periods offer pleasant weather, with moderate temperatures and less humidity than the peak summer months. You'll find it comfortable for walking around and exploring the area's amenities. Additionally, these shoulder seasons generally mean fewer crowds compared to the busiest summer travel period, leading to a more relaxed experience.

For those visiting for medical appointments, these months also generally provide a calmer environment around the hospitals and clinics.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Medical Center Area hotel for you.
How can I save on a Medical Center Area hotel booking with Expedia?
With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Medical Center Area hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings.
How much is the nightly rate at a Medical Center Area hotel?
Hotel prices in Medical Center Area often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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